Warframe
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Table of contents

Complete Guide to the Patient Zero Quest in Warframe

Introduction

In Warframe, the Patient Zero quest is a fascinating narrative arc that delves into the mysterious origins of the Infested. This quest not only challenges your combat skills but also unveils important lore about the game's universe. This guide will provide you with a detailed, step-by-step walkthrough to navigate through this quest efficiently.

Step-by-Step Walkthrough

  • Starting the Quest

    • To begin the Patient Zero quest, you must first have completed the quest "The Second Dream".
    • Access the Quest from your Codex in your ship; it will appear in the "Quests" tab.
    • Select "Patient Zero" and confirm to start the mission.

  • Mission 1: Derelict - Investigate the Infested Ship

    • Head to the Derelict and prepare for combat; make sure you have proper gear and mods equipped.
    • Proceed to the marked location; you will face various Infested enemies.
    • Tip: Use area-of-effect weapons or abilities to deal with the hordes quickly.
    • Once you reach the infested ship's entrance, interact with the console to collect data logs.

  • Mission 2: Defeat the Infested Boss - The Infected Bounty

    • After collecting the data logs, you will confront the Infested Boss known as the Infected Bounty.
    • Move quickly and use your Warframe's abilities strategically to avoid taking damage.
    • Strategy: Focus on crowd control by eliminating minions first before tackling the boss.
    • Upon defeating the boss, collect any special items they drop, which are crucial for crafting.

  • Mission 3: The Search for Patient Zero

    • Next, you will need to search for clues leading to Patient Zero.
    • Follow the map markers to find clues and gather information on nearby enemies.
    • Be prepared for ambushes as you gather information; use stealth to pick off isolated enemies when necessary.
    • Collect all the clues and return to your ship.

  • Mission 4: The Encounter with Patient Zero

    • The final phase of the quest will lead you to an intense encounter with Patient Zero itself.
    • Ensure your equipment and health are optimized before proceeding; this battle requires focus.
    • Boss Fight Tips:
      • Use elemental damage types your Warframe is strong against.
      • Manage your energy to use abilities effectively throughout the fight.
      • Watch out for Patient Zero's special attacks and patterns; dodge at the right moments to minimize damage.
    • After you defeat Patient Zero, you will unlock more lore and insights about the Infested.

  • Mission Completion and Rewards

    • After the final fight, return to your ship.
    • You will receive rewards based on your performance, including experience points and unique items relevant to the quest.
    • Check your inventory to see if you've acquired any new mods, blueprints, or crafting materials.

Conclusion

Completing the Patient Zero quest in Warframe not only enriches your understanding of the game's lore but also provides substantial rewards for your efforts. By following this detailed walkthrough, you'll be well-prepared to tackle the challenges presented throughout the quest and emerge victorious. Enjoy your journey, Tenno!